Selank
Selank – 10mg, Reagent Grade
Premium-quality Selank peptide (10 mg) supplied in lyophilized powder form. Extensively researched for its potential roles in cognitive function, mood regulation, and neuroprotection. For laboratory research use only
Original price was: $48.00.$40.00Current price is: $40.00.
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Features & Compatibility
Selank for sale – Synthetic Heptapeptide Anxiolytic
What is Selank?
Selank for sale is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the naturally occurring immunomodulatory peptide tuftsin. It is classified as a nootropic and anxiolytic peptide with potential applications in neuropsychiatry, cognitive enhancement, and stress modulation research. Selank for sale has gained attention for its unique profile of modulating GABAergic and monoaminergic neurotransmission without causing sedation or dependence.
Product Summary – Selank for sale
| Field | Details |
| Product Name | Selank for Sale (Thr-Lys-Pro-Arg-Pro-Gly-Pro; TKPRPGP) is a synthetic analogue of tuftsin. |
| Category | Synthetic neuropeptide (heptapeptide); anxiolytic, nootropic, and immunomodulatory agent developed in Russia. |
| Length | 7 amino acids (heptapeptide). |
| Amino Acid Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro. |
| Molecular Formula & Weight | Detailed chemical identifiers are beyond current literature summaries. |
| Form & Purity | Typically provided as lyophilised powder for research; purity is usually >95% by HPLC per vendor standards (confirm per lot). |
| Storage | Store dry at −20 °C; reconstituted solutions should be refrigerated and used promptly. |
| Key Mechanisms of Action | – Acts as a positive allosteric modulator of GABA_A receptors, influencing GABA binding and modulating gene expression in neurotransmission pathways.
– Alters expression of genes tied to neurotransmission, including monoamine and dopamine receptor genes and sleep/wake regulation. – Enhances BDNF expression in rodents, improves cognitive performance in learning/memory tasks, and protects against alcohol withdrawal–induced cognitive deficits. – Demonstrates immunomodulatory effects by reducing elevated pro-inflammatory cytokines (IL-1β, IL-6, TNF-α, TGF-β1) under stress. |
| Research / Clinical Use Cases | – Anxiolytic and psychostimulant effects in generalised anxiety and neurasthenia—comparable to benzodiazepines but without sedation, tolerance, or dependence.
– Combined use with benzos enhances anxiolytic effects and may reduce required benzodiazepine dosing. – Improves resting-state functional connectivity (e.g. right amygdala connectivity) in healthy individuals. |
| Common AEs / Safety Signals | High safety profile in animals and limited human use. Adverse effects: mild nasal irritation, headache, fatigue, rare overstimulation; no tolerance or withdrawal reported. |
| Contraindications / Warnings | Not FDA-approved. Used intranasally; safety in pregnancy, lactation, or polypharmacy not established. Use only under research supervision. |
| Regulatory / Compliance | Available as research or compounding products in Russia and some Eastern European countries; unregulated in the U.S. and most other jurisdictions. |
Mechanism of Action | Selank for sale
Selank exhibits a multimodal mechanism, making it of significant interest in neuropsychopharmacology research:
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GABAergic Modulation—Enhances GABA receptor binding, mimicking benzodiazepine-like anxiolysis but without sedative drawbacks.
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Monoamine Regulation—Normalises dopamine and serotonin metabolism, contributing to mood stabilisation.
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Neurotrophic Effects—Increases expression of brain-derived neurotrophic factor (BDNF), supporting synaptic plasticity and cognitive enhancement.
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Immunomodulatory Action—Derived from tuftsin, it modulates cytokine release and may balance immune response under stress conditions.
Research Applications
Selank is being investigated for diverse preclinical and early clinical research domains, including:
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Anxiety & Stress Disorders—Non-sedative anxiolytic effects comparable to benzodiazepines but without withdrawal risk.
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Depression Research—Potential adjunct in mood regulation studies through monoamine modulation.
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Cognitive Performance—Enhanced learning, memory, and concentration under experimental conditions.
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Neuroprotection—possible role in protecting neurones against oxidative stress and ischaemia-related injury.
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Immunology – Ongoing research into its immunomodulatory role in balancing pro- and anti-inflammatory responses.
Safety & Tolerability
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Non-Sedative – Unlike benzodiazepines, Selank for Sale does not impair motor skills or induce drowsiness.
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Non-Addictive Profile – No reported risk of tolerance or dependency in clinical research studies.
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Well-Tolerated – Preclinical and limited clinical data suggest low toxicity and favourable safety margins.
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Side Effects (Research Reports) – Mild headache, nasal irritation (intranasal administration), and rare transient fatigue.
✅ Note: Selank for sale is for research purposes only and is not approved for human therapeutic use.
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